Table 1.

Impact of obesity on response to therapy

Research article first author	Number of subjects	Obese (%)	Outcome	Effect size (OR)	95% CI	P value
Di Minno et al. (2013)	270	135 (50%)	Probability of not achieving MDA in obese vs normal patients	4.9	3.04–7.87	<0.001
Eder et al. (2014)	557	197 (35.4%)	Probability of achieving MDA in obese vs normal patients	0.52	0.4–0.67	<0.001
Ogdie et al. (2019)	774	428 (55%)	Predictor of CDAI remission in BMI > 30 vs ≤ 30	0.51	0.32–0.81
Di Minno et al. (2014)	126	126 (100%)	Probability of achieving MDA with 5–10% vs < 5% weight loss	3.75	1.36–10.36	0.011

OR odds ratio