Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jul 31;8:891. doi: 10.3389/fbioe.2020.00891

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Oliveira, Pieters, Guimarães, Duffles, Heredia, Silveira, Oliveira, Teixeira, Ferreira, Silva, van de Loo and Macari.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Effect of milk extracellular vesicle treatment on histological analyses of femur and osteoclast differentiation in vitro. (A) Osteoclast number over the bone surface area (N.Oc/BS) and representative histology of distal femur stained with TRAP (40× and 200×). Green arrows indicate osteoclasts. (B) The number of TRAP–positive cells/well and representative images of TRAP–positive cells in the culture (100×). Analyses were performed in mice (i) pseudo-operated (SHAM) or (ii) ovariectomized (OVX), (iii) non-treated (control), or (iv) treated with milk extracellular vesicles (mEVs). Values are means ± SEM of 6–8 animals per group. * vs. respective SHAM group and # vs. non-treated group.