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. 2020 Aug 6;10:13248. doi: 10.1038/s41598-020-70269-7

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Meta‐analyses for the association of anti-VEGF and RNFL-thickness. Black diamonds indicate the overall WMD. The size of the gray box is inversely proportional to the variance. Horizontal lines indicate 95% CI. The vertical line in each panel shows the value for no effect (WMD = 0). RNFL retinal nerve fiber layer, WMD weighted mean difference, I 3 months post-injection, II 6 months, III 12 months, IV at end of follow-up.