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. 2020 Aug 6;10:13290. doi: 10.1038/s41598-020-70003-3

Table 2.

Baseline characteristics and short-term morbidities across GMs trajectories.

Demographic features N-N (n = 128) PR-N (n = 17) N-PR (n = 12) PR-PR (n = 50) PR-CS (n = 5) CS-CS (n = 4) p.value
Gestational age at birth (weeks), mean ± SD 30.0 (2.1) 28.4 (2.1) 29.6 (1.6) 28.1 (2.2) 27.5 (1.7) 27.6 (3.2)  < 0.001a
Birth weight (g), mean ± SD 1,188 (236) 1,006 (230) 1,117 (258) 996 (289) 954 (391) 1,030 (333)  < 0.001a
Male, n (%) 49 (38) 6 (35) 8 (67) 29 (58) 3 (60) 2 (50) 0.035c
Twins, n (%) 60 (47) 9 (53) 3 (25) 27 (55) 1 (20) 0 (0) 0.298c
Monochorionic twins, n(%) 28 (47) 6 (67) 2 (67) 8 (30) 1 (100) 0 (100) 0.164c
Apgar score at 1’, median (range) 7 (1–9) 7 (2–8) 8 (4–9) 6 (2–9) 5 (3–7) 4 (1–6)  < 0.001b
Apgar score at 5’, median (range) 8 (5–10) 8 (5–9) 9 (6–10) 8 (6–10) 7 (6–8) 8 (3–9) 0.032b
Cesarean section, n (%) 115 (91) 13 (76) 9 (75) 46 (94) 5 (100) 4 (100) 0.060c
Small for gestational age, n (%) 27 (21) 2 (12) 2 (17) 10 (20) 1 (20) 0 (0) 0.882c
Days of hospitalization, median (IQr) 55 (44; 70)

72

(56; 84)

68 (59; 84) 99 (54; 127) 92 (79; 99) 96 (78; 147)  < 0.001b
Severe brain lesion, n (%) 5 (4) 2 (12) 2 (17) 11 (22) 5 (100) 4 (100)  < 0.001c
Other comorbidities, n (%) 20 (16) 4 (24) 3 (25) 23 (46) 3 (60) 3 (75)  < 0.001c
Maternal age, mean ± SD 35.0 (5.3) 32.1 (6.7) 33.2 (7.5)

34.8

(6.7)

36.8 (4.1) 30.3 (5.7) 0.237a

Persistence of normal pattern (N-N), early poor repertoire followed by a normal pattern (PR-N), early normal followed by a poor repertoire pattern (N-PR), persistence of poor repertoire pattern (PR-PR), early poor repertoire followed by cramped synchronized pattern (PR-CS), persistence of cramped synchronized pattern (CS-CS).

aOne way ANOVA.

bKruskal Wallis test.

cFisher’s exact test.