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. 2020 Aug 6;10:13303. doi: 10.1038/s41598-020-70145-4

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The template for Replication Initiation and Replication Elongation processes. The network depicted shows three steps of Replication Elongation going both chromosome directions. The dashed lines mask the rest of the process and go straight to the final reaction, where the terminus region (2206) is replicated and the Replisomes released. The actual molecules’ IDs in the network are listed in the Supplementary Information. Although some stoichiometries are shown, most of them are hidden for better visualization.