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. 2020 Jul 31;11:1183. doi: 10.3389/fphar.2020.01183

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Copyright © 2020 Li, Xue, Xiang, Song, Yan, Ji, Zhu, Wei and Yu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of high serine condition on cell migration and invasion of MGC803 and HGC27 cells. (A) The enhancing effect on cell migration and invasion under high serine condition. High serine in medium significantly promotes migration and invasion of HGC27 and MGC803 cells. Incubation with chemical cryptotanshinone suppresses cell migration and invasion. (B) Comparison of the difference on cell migration between HGC27 and MGC803 cells under the same cell culture conditions. (C) Comparison of the difference on cell invasion between HGC27 and MGC803 cells under the same cell culture conditions. These data are representative examples taken from one of the three experiments. "***" and "****" represent P < 0.001, and P < 0.0001, compared to normal group. "^####" represent P < 0.0001, compared to high-serine group.