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. 2020 Jul 31;11:848. doi: 10.3389/fgene.2020.00848

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Copyright © 2020 Zhu, Guo, Zhao, Qiao, Han, Liu, Yuan, Wang, Li, Yue and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Manhattan plots of haplotype-based analysis for six erythrocyte traits. Chromosomes 1 to 26 are shown in different colors; the horizontal dotted green line and solid line indicate the suggestive and genome-wide significance level, respectively. Haplotypes surpassing the genome-wide threshold are highlighted in red, and haplotypes reaching the suggestive threshold are highlighted in green. The strips below each chromosome indicate the density of the markers. The six traits were: red blood cell count (RBC), hemoglobin (HGB), hematocrit (HCT), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), and RBC volume distribution width coefficient of variation (RWD_CV).