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. 2020 Jun 30;22(3):1759–1766. doi: 10.3892/mmr.2020.11291

Figure 3.

Figure 3.

Atrial structural remodeling of fibrosis. (A) Representative Masson's trichrome staining sections of the four groups. Scale bar, 100 µm. (B) CVF (%) in the four groups. (C) TGF-β mRNA expression in the four groups. (D) Collagen I mRNA expression in the four groups. (E) CF proliferation rate of the four groups. (F) CF migration rate of the four groups. n=20 for each group. Data are presented as mean ± SD. *P<0.05 and ****P<0.0001 vs. the control group; ##P<0.01 and ####P<0.0001 vs. the DM group; ++P<0.01 vs. the H2S group. Fold-change means the value compared with the control group. CF, cardiac fibroblasts; CVF, collagen volume fraction; TGF-β, tumor growth factor β; DM, diabetes mellitus; H2S, hydrogen sulfide.