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. 2020 Jun 23;22(3):2052–2062. doi: 10.3892/mmr.2020.11266

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Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Expression levels of inflammatory factors, mitochondrial damage and cardiac hypertrophic failure in a myocardial infarction rat model. (A) Effects of statin rosuvastatin on the protein levels of MMP-9, TNF-α, NF-κB and IL-1β in heart tissue. (B) Effects of statin on anti-inflammatory cytokine IL-10 in heart tissue. (C) Effects of statin on cytosolic Cytochrome c expression in heart tissue. (D) Effects of statin on PGC-1α, BNP and α-MHC expression in heart tissue. **P<0.01. MMP, matrix metalloproteinase; TNF, tumor necrosis factor; NF-κΒ, nuclear factor κΒ; IL, interleukin; PGC, peroxisome proliferator-activated receptor γ coactivator; BNP, brain natriuretic peptide; α-MHC, α myosin heavy chain.