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. 2020 Jul 31;11:1675. doi: 10.3389/fimmu.2020.01675

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Copyright © 2020 Chen, Huang, Chen, Wu, Hsu, Tsai, Ko and Tsai.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Sufficient cholesterol is essential for C. difficile and SLPs-induced inflammasome activation. Western blot analysis of (A) IL-1β maturation either in cell lysate or supernatant after SLPs treatment, and (B) C. difficile infection.