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. 2020 Jun 18;22(3):2032–2042. doi: 10.3892/mmr.2020.11254

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Copyright: © Zou et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 8. — Genistein treatment upregulates the protein expression levels of collagen II, aggrecan and ERα, and downregulates caspase 3 expression. (A) Western blotting of samples from the experimental groups using the indicated antibodies. Semi-quantitative analyses of the (B) collagen II/GAPDH, (C) aggrecan/GAPDH, (D) caspase 3/GAPDH and (E) ERα/GAPDH ratios. Data are presented as the mean ± SD (n=10). *P<0.05, **P<0.01 vs. the normal group; ^#P<0.05, ^##P<0.01 vs. the OA group. ERα, estrogen receptor; OA, osteoarthritis.