Table 1.
Description of the maximum likelihood estimate of the pattern of nucleotide substitution in the five melatonin biosynthesis genes. Each entry is the probability of substitution from one base (row) to another base (column). Rates of different transitional substitutions are shown in bold and the rest for transversional substitutions.
| Gene | Nucleotide Substitution Matrix | ||||
|---|---|---|---|---|---|
| A | T | C | G | ||
| ASMT1 | A | - | 5.31 | 4.17 | 13.63 |
| T | 5.55 | - | 13.47 | 4.58 | |
| C | 5.55 | 17.17 | - | 4.58 | |
| G | 16.51 | 5.31 | 4.17 | - | |
| ASMT2 | A | - | 5.88 | 4.09 | 12.04 |
| T | 6.50 | - | 11.96 | 4.86 | |
| C | 6.50 | 17.22 | - | 4.86 | |
| G | 16.12 | 5.88 | 4.09 | - | |
| ASMT3 | A | - | 6.40 | 4.06 | 12.48 |
| T | 6.36 | - | 10.91 | 5.08 | |
| C | 6.36 | 17.80 | - | 5.08 | |
| G | 15.63 | 6.40 | 4.06 | - | |
| T5H | A | - | 6.39 | 4.09 | 12.32 |
| T | 6.40 | - | 10.98 | 5.02 | |
| C | 6.40 | 17.18 | - | 5.02 | |
| G | 15.72 | 6.39 | 4.09 | - | |
| TDC | A | - | 8.33 | 8.33 | 8.33 |
| T | 8.33 | - | 8.33 | 8.33 | |
| C | 8.33 | 8.33 | - | 8.33 | |
| G | 8.33 | 8.33 | 8.33 | - | |
A = adenine, T = thymine, C = cytosine, G = guanine, ASMT = N-acetylserotonin methyltransferase, T5H = tryptamine 5-hydroxylase, and TDC = tryptophan decarboxylase.