Table 1.
Sample Name | Microbial Organism | |||
---|---|---|---|---|
MRSA | S. aureus | E. coli | C. albicans | |
myristic acid (1) | >1000 | >1000 | >1000 | >1000 |
stigmasterol (2) | >1000 | 62.50 | 15.63 | >1000 |
sesamin (3) | >1000 | 500 | >1000 | >1000 |
8- acetonyldihydrochelerythrine (4) | 31.25 | 15.63 | 15.63 | 62.50 |
arnottianamide (5) | >1000 | >1000 | >1000 | >1000 |
10-methoxycanthin-6-one (6) | 3.91 | 1.95 | 3.91 | 7.81 |
canthin-6-one (7) | 0.98 | 0.49 | 1.95 | 3.91 |
8-oxochelerythrine (8) | 62.50 | 7.81 | 3.91 | 15.63 |
Z. paracanthum root bark extract | 3.91 | 0.98 | 1.95 | 7.81 |
Omacilin | 0.98 | 0.49 | 0.98 | - |
Fluconazole | - | - | - | 1.95 |
MIC—Minimal inhibition concentration. MRSA—methicillin resistant Staphylococcus aureus, Escherichia coli (ATCC 25922), Staphylococcus aureus (ATCC 29213) and Candida albicans (ATCC 10231). MIC values for canthin- 6- one (7) against MRSA and S. aureus were similar to omacilin (positive control).