Table 4.
ECCO2R treatment initiation criteria for patients with ae-COPD
| Initiation criteria for patients at risk of NIV failure | |
| Parameter | |
| No decrease in PaCO2 while on NIV | Consensus |
| No decrease in respiratory rate while on NIV | Consensus |
| Clinical signs of respiratory failure | Majority agreement |
| pH 7.25–7.30 | Majority agreement |
| Baseline PaCO2 | No agreement |
| Baseline respiratory rate | No agreement |
| Initiation criteria for patients who are already intubated | |
| - Patients who look like they will not be extubated early without ECCO2R | |
| ○ Previous intubation for ae-COPD | |
| ○ Has failed a spontaneous breathing trial due to increased dyspnoea | |
| ○ Reintubation after first extubation attempt despite NIV | |
| ○ Patients with severe bronchospasm who are difficult/impossible to ventilate adequately or otherwise not responding to medical treatment | |
| ○ Patients who remain hypercapnic and not improving with MV | |
| - No hypoxemia preventing extubation | |
| - MV < 72 h | |
| - Patients with home NIV and good quality of life | |
Criteria for ECCO2R treatment considered to be of importance and selected from the provided list. Target describes any potential target values identified. Consensus means a consensus threshold (≥ 80%) was reached, majority agreement means ≥ 50% agreed but consensus level was not reached, and no agreement means < 50% agreed
Scoring and ranking was not conducted for this section during the meeting