Table 9.

Univariate and multivariate Cox proportional hazards regression analysis for DFS

Variables	Univariate			Multivariate
	HR	95% CI	P‐values	HR	95% CI	P‐values
Therapy			.757
Untreated	Ref.
Chemotherapy	1.008	0.000‐4.37E+07	.999
Radiotherapy	21.961	0.000‐5.20E+07	.680
Sex	1.345	0.694‐2.604	.380
Female	Ref.
Male
Age	1.080	0.548‐2.130	.824
<60	Ref.
≥60
T			.247
T1	Ref.
T2	0.810	0.214‐3.064	.756
T3	1.442	0.412‐5.043	.567
T4	1.837	0.541‐6.238	.330
N			.664
N0	Ref.
N1	0.704	0.157‐3.148	.646
N2	0.895	0.271‐2.960	.856
N3	1.329	0.363‐4.872	.668
M	3.672	1.886‐7.149	.000	2.862	1.419‐5.773	.003
M0	Ref.			Ref.
M1
Histology			.771
Keratinizing*	Ref.
Non‐Keratinizing#	2.318E+04	0‐5.518E+110	.936
Unknown	3.620E+04	0‐1.516E‐102	.933
PLR	2.948	1.557‐5.581	.001	2.250	1.153‐4.394	.017
<245.496	Ref.			Ref.
≥245.496