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Analysis of the anti-IAV activity of combination treatment with oseltamivir and itraconazole. Polarized Calu-3 monolayers were infected with 0.1 MOI of (a) pdm09 or (b) Panama for 24 h. Oseltamivir and itraconazole were added at the indicated combinations 2 h p.i. Mean percentages of reduction in viral titers ± SEM, with mean virus titer in control cells (treated with the solvent DMSO) set to 100%; n = 3. Dotted line, 90% reduction in viral titer.
