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. 2020 Jul 3;25(13):3047. doi: 10.3390/molecules25133047

Table 6.

List of the lipid removal methodologies.

Matrix Technique Effectiveness References
Porcine muscle-milk LLE with hexane [184,185]
High lipid foodstuff Freezing lipid precipitation (LFP) Effective sample clean-up [186]
Milk Lipid precipitation by zinc and tungsten salt solutions in acidic media Good sensitivity [187,188]
Milk Dispersive solid phase extraction (d-SPE) by using a combination of PSA-C18 solid sorbent or PSA- Zirconium-dioxide Very effective ME reduction [189,191]
Fish muscle- Breast Milk Protein-lipid removal filter cartridges (Captiva ND Lipids) The best option to reduce ME in LC-MS applications. Effective also in protein removal [172]