Table 1.
Baseline characteristics of the population
| Non-COPD (n = 30) | COPD (n = 28) | p-value | |
|---|---|---|---|
| Sex ratio H/F | 13/17 | 17/11 | ns |
| Age (years) | 53.9 ± 15.3 | 62.1 ± 10.6 | ns |
| Smoking history | 0.009 | ||
| Never smokers | 8 (27%) | 0 | |
| Current-smokers | 12 (40%) | 12 (43%) | |
| Former-smokers | 10 (33%) | 16 (57%) | |
| Pack-years | 21 ± 21 | 41 ± 22 | < 0.001 |
| Spirometry | |||
| FEV1, % of predicted value | 97 ± 19 | 55 ± 25 | < 0.0001 |
| FVC, % of predicted value | 100 ± 18 | 82 ± 20 | 0.003 |
| FEV1/FVC % | 81 ± 9 | 49 ± 12 | < 0.0001 |
| Spirometric GOLD 1/2/3/4 | NA | 7/6/9/6 | – |
| GOLD ABCD (mMRC) | NA | 8/6/6/8 | – |
| GOLD ABCD (CAT) | NA | 7/7/4/10 | – |
| Frequent exacerbation (> 1/year) | – | 10 (36%) | – |
Data are expressed as mean ± SD or number (%) FEV1 forced expiratory volume in 1 s, FVC forced vital capacity, mMRC modified medical research council, CAT COPD assessment test
ns: non-significate