Skip to main content
. 2020 Aug 6;21:196. doi: 10.1186/s13059-020-02096-y

Table 3.

The alternative hypothesis HA:pg>eλ is robust to different model hypotheses

Underlying distribution p under H0 p under HA
Mixture of Poisson eλ=ekπkλk kπkeλk
Negative binomial eλ rr+λr
Zero-inflated negative binomial eλ rr+λr+π0

In the first row, the right column is larger than the left column due to Jensen’s inequality. For negative binomial, the dispersion parameter r is constructed so that the variance is λ2r+λ, so that Poisson is a special case of negative binomial with r=. The zero-inflated negative binomial distribution is parameterized as π0δ0+(1−π0) NB(λ,r)