FIGURE 2.

Down‐regulated miR‐3677‐3p inhibits metastasis, invasion and proliferation of HCC in vitro. A, MHCC‐97H and SMMC‐7721 cells that were transfected with the corresponding miRNA inhibitor were subjected to qRT‐PCR for evaluation of miR‐3677‐3p expression. B, CCK‐8 tests showed lower cellular vitality in both cell lines transfected with miR‐3677‐3p inhibitor. C, The proportion of EDU in two cell lines transfected with miR‐3677‐3p inhibitor was lower than in the NC group. Bar figures indicate the statistics. D, Cell migration and invasion as measured by Transwell assays were inhibited by knock‐down of miR‐3677‐3p in MHCC‐97H and SMMC‐7721 cells. Bar figures indicate the statistics. n = 4 independent experiments. *P < .05, **P < .01