FIGURE 6.

SIRT5 is down‐regulated in HCC and regulates the migration and invasion of HCC. A, CCK‐8 tests showing a lower cellular vitality in Hep3B cell lines transfected with pcDNA‐SIRT5. B, The proportion of EDU in Hep3B cells transfected with pcDNA‐SIRT5 was lower than in the NC group. Bar figures indicate the statistics. C, Cell migration and invasion as measured by Transwell assays were inhibited by up‐regulated expression of SIRT5 in Hep3B cells. Bar figures indicate the statistics. n = 4 independent experiments. *P < .05