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. 2020 Jul 25;18:2033–2042. doi: 10.1016/j.csbj.2020.07.013

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© 2020 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Fig. 4 — DCCMs of wild-type (top-left) and KDM6A mutants. Perfect correlations are highlighted in red (direct) or violet (inverse). Boxes in the wild-type DCCM highlight: (blue) the JmjC region spanning residues from 1078 to 1268, describing correlated and anticorrelated motions with the linker domain region (residues 910–933); (red) the N-terminal region of JmjC (935–985) correlates with the C-terminal region (1078–1268); (violet) the region spanning residues 1048 to 1077 correlates with the whole JmjC domain; (green) correlated internal subregions of the JmjC domain.