Fig. 8. Lowest-energy docking conformation of sulfonamide 2a docked into the active site of CphA (PDB code ; 2QDS). The enzyme backbone is shown as a cartoon in green, and selected residues are shown as sticks colored by elements (H, white; C, yellow; N, blue; O, red; S, orange). The Zn(ii) ion is shown as a magenta sphere; 2a is shown as sticks with the same color code as amino acid residues. Characteristic short distances between the inhibitor and the protein are indicated by dashed lines. These figures were generated with PyMOL.