. 2020 Jan 10;11(2):259–267. doi: 10.1039/c9md00455f

Table 2. MICs of carbapenems, imipenem (A) and meropenem (B), against E. coli BL21 (DE3) cells expressing ImiS in the absence and presence of benzenesulfonamides at a concentration of 16 μg mL^–1 ^a .

A
Compd.	1a	1b	1c	1d	1e	1f	1g	1h	1i	1j
MIC	8	8	8	8	8	8	8	8	8	8
Compd.	2a	2b	2c	2d	2e	2f	2g	2h	3e	3f	RS
MIC	4	4	4	4	4	4	4	4	8	8	8

B
Compd.	1a	1b	1c	1d	1e	1f	1g	1h	1i	1j
MIC	32	32	32	32	32	32	32	32	32	32
Compd.	2a	2b	2c	2d	2e	2f	2g	2h	3e	3f	RS
MIC	16	16	16	16	16	16	16	16	32	32	32

^aMICs of imipenem and meropenem alone on E. coli BL21 (DE3) with ImiS were 16 and 64 μg mL^–1, respectively. The MICs of imipenem and meropenem on E. coli without ImiS in the absence and presence of benzenesulfonamides were 0.25 and 0.0375 μg mL^–1, respectively.

Table 2. MICs of carbapenems, imipenem (A) and meropenem (B), against E. coli BL21 (DE3) cells expressing ImiS in the absence and presence of benzenesulfonamides at a concentration of 16 μg mL–1 a .

Table 2. MICs of carbapenems, imipenem (A) and meropenem (B), against E. coli BL21 (DE3) cells expressing ImiS in the absence and presence of benzenesulfonamides at a concentration of 16 μg mL^–1 ^a .