Table 2.

Univariate and multivariate Cox regression models for overall survival.

Variable		Univariate model				Full multivariate model				Reduced multivariate model
		HR	95% CI		P	HR	95% CI		P	HR	95% CI		P
Patients' risk	Sex				0.565
	Female	Ref
	Male	1.05	0.89	1.25	0.565
	Age, year				0.002				0.003				0.003
	<65	Ref				Ref				Ref
	≥65	1.27	1.09	1.48	0.002	1.29	1.09	1.53	0.003	1.29	1.09	1.52	0.003
	BMI				<0.001				0.003				0.004
	<18.5	Ref				Ref				Ref
	18.5–24.9	0.60	0.49	0.75	<0.001	0.74	0.59	0.91	0.006	0.74	0.59	0.92	0.007
	≥25.0	0.50	0.37	0.66	<0.001	0.60	0.45	0.81	0.001	0.61	0.45	0.82	0.001
	Medical insurance type				0.046
	Self-paid	Ref
	Rural insurance	0.71	0.56	0.91	0.006
	Urban insurance	0.73	0.57	0.94	0.015
	Others	0.95	0.35	2.60	0.923
	Occupation				0.872
	No	Ref
	Yes	1.03	0.74	1.43	0.872
	Income				0.218
	Very low	Ref
	Low	0.86	0.71	1.04	0.121
	General	0.96	0.76	1.22	0.745
	High	0.66	0.39	1.12	0.124
	Social status				0.426
	Very low	Ref
	Low	0.99	0.52	1.87	0.978
	General	0.88	0.47	1.65	0.692
	High	0.73	0.37	1.46	0.375
	Very high	0.91	0.40	2.11	0.832
	Residential address				0.745
	Village	Ref
	City	0.98	0.84	1.14	0.745
	Marital status				0.515
	No	Ref
	Yes	0.80	0.42	1.55	0.515
	Procreation status				0.209
	No	Ref
	Yes	0.68	0.38	1.24	0.209
	Smoking and drinking consumption				0.312
	No	Ref
	Smoking	0.88	0.72	1.06	0.167
	Drinking	1.26	0.83	1.90	0.273
	Both	0.95	0.75	1.21	0.683
	ASA score				0.043				0.002				0.002
	I	Ref				Ref				Ref
	II	1.10	0.94	1.29	0.252	1.24	0.98	1.58	0.072	1.25	0.98	1.59	0.068
	III–IV	1.51	1.08	2.11	0.016	2.09	1.39	3.15	<0.001	2.09	1.38	3.14	<0.001
	Abdominal surgery history				0.675
	No	Ref
	Yes	1.05	0.84	1.31	0.675
	Intra-abdominal surgery history				0.615
	No	Ref
	Yes	1.07	0.81	1.41	0.615
	Comorbidity				<0.001				0.043				0.040
	No	Ref				Ref				Ref
	Yes	1.47	1.23	1.76	<0.001	1.32	1.01	1.72	0.043	0.76	0.58	0.99	0.040
Tumor's risk	Tumor site				<0.001				0.111				0.098
	Lower	Ref				Ref				Ref
	Middle	1.27	1.03	1.57	0.023	1.18	0.96	1.47	0.122	1.18	0.95	1.46	0.126
	Upper	1.12	0.92	1.36	0.280	1.06	0.86	1.30	0.589	1.06	0.86	1.29	0.591
	Overlapping lesion of stomach	1.91	1.53	2.38	<0.001	1.32	1.04	1.68	0.024	1.33	1.05	1.69	0.020
	pTNM stage				<0.001				<0.001				<0.001
	IIA	Ref				Ref				Ref
	IIB	1.24	0.86	1.80	0.248	1.21	0.83	1.76	0.320	1.23	0.84	1.78	0.288
	IIIA	1.72	1.21	2.43	0.002	1.67	1.17	2.37	0.005	1.69	1.19	2.41	0.004
	IIIB	3.08	2.27	4.19	<0.001	2.81	2.04	3.86	<0.001	2.91	2.13	3.99	<0.001
	IIIC	5.41	4.02	7.28	<0.001	4.42	3.22	6.08	<0.001	4.64	3.39	6.34	<0.001
	Tumor size, mm				<0.001				0.013				0.012
	<20	Ref				Ref				Ref
	20–50	1.37	0.78	2.38	0.272	1.00	0.57	1.77	0.997	1.01	0.57	1.78	0.975
	>50	2.60	1.50	4.53	0.001	1.29	0.73	2.28	0.385	1.30	0.73	2.29	0.370
	Lymphatic vessel infiltration				<0.001				0.231
	Negative	Ref				Ref
	Positive	1.32	1.14	1.54	<0.001	1.10	0.94	1.29	0.231
	Pathological differentiation degree				0.001				0.172
	Differentiated	Ref				Ref
	Undifferentiated	0.72	0.60	0.87	0.001	0.87	0.71	1.06	0.172
Treatment risk	Examined LNs, no.				<0.001				<0.001				<0.001
	>15	Ref				Ref				Ref
	≤ 15	2.15	1.47	3.14	<0.001	2.82	1.90	4.19	<0.001	2.72	1.84	4.03	<0.001
	Clavien–Dindo grade				<0.001				0.037				0.033
	None	Ref				Ref				Ref
	I–II	1.41	1.14	1.74	0.001	1.29	1.04	1.60	0.023	1.29	1.04	1.60	0.022
	III–IV	1.64	1.21	2.23	0.002	1.27	0.93	1.75	0.139	1.28	0.93	1.77	0.124
	Chemotherapy				<0.001				0.003				0.004
	AC group	Ref				Ref				Ref
	UAC group	1.48	1.27	1.73	<0.001	1.29	1.09	1.52	0.003	1.28	1.08	1.51	0.004

AC, Acceptable chemotherapy; UAC, unacceptable delay or missing chemotherapy; LN, lymph node; HR, hazard ratio.

Bold values indicates P < 0.05, statistically significant.