Injection of Exosomes from ADSCs Overexpressing SIRT1-Induced Vasculogenesis
(A and B) Arteriole density from α-SMA staining. Representative images (A, Scale bars, 100 μm.) and quantification (B) of arteriole density in the peri-infarcted myocardium at 28 days after AMI, analyzed by α-SMA staining. #p < 0.05; ##p < 0.01, compared with the AMI + vehicle group; &p < 0.05, compared with the AMI + ADSCs-Exos group; n = 6 per group. (C and D) Capillary density from vWF-positive vessels; representative images (C, Scale bars, 100 μm.) and quantification (D). The blood vessel density is indicated as the vessel number per square millimeter. #p < 0.05; ##p < 0.01, compared with the AMI + vehicle group; &p < 0.05, compared with the AMI + ADSCs-Exos group; n = 6 per group.