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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Med Phys. 2019 Sep 26;46(11):5134–5143. doi: 10.1002/mp.13803

FIG. 6.

FIG. 6.

Retrieval specimen analysis from five in-vivo tumor samples. Sufficient tissue was retrieved for analysis in all five samples. The average number of drug sites assessed for each sample was 6.8 (minimum 5, maximum 10) and average tissue thickness at the drug delivery sites was 553.3 um (minimum 218.2, maximum 938.1). Drug delivery to apoptotic response spatial correlation was seen in all tumors, indicating therapeutic efficacy in the tested A375 and MC38 animal models. *Specimen 5 separated from the microdevice during processing; drug delivery location was still able to be assessed by identifying the area of fluorescent doxorubicin signal.