Table 4.
Factors | Univariate analysis | Multivariate analysis | |||
---|---|---|---|---|---|
Average survival time | P a | HR | 95% CI | P b | |
Sex | |||||
Female | 56.8 | .124 | |||
Male | 46.7 | ||||
Age | |||||
<60 | 52.5 | .784 | |||
≥60 | 50.2 | ||||
Tumor size, cm | |||||
≤5 | 55.9 | .007 | 1 | ||
>5 | 37.1 | 1.32 | 0.92-1.89 | .136 | |
Histological grade | |||||
I+II | 51.7 | .606 | |||
III | 45.7 | ||||
T stage | |||||
I+II | 56.3 | <.001 | 1 | ||
III+IV | 29.2 | 1.48 | 0.99-2.20 | .056 | |
N stage | |||||
N0 | 64.6 | <.001 | 1 | ||
N1-N3 | 36.9 | 1.80 | 1.27-2.54 | .001 | |
TNM stage | |||||
I | 68.1 | <.001 | |||
II | 49.4 | ||||
III | 25.6 | ||||
ALDH3B1 | |||||
Low | 60.1 | .004 | 1 | ||
High | 43.3 | 1.56 | 1.13-2.17 | .007 |
Abbreviations: ALDH3B1, aldehyde dehydrogenase 3B1; TNM, tumor–node–metastasis.
a Calculated by the log-rank test.
b Means calculated by the Cox-regression model.