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. Author manuscript; available in PMC: 2020 Dec 19.
Published in final edited form as: Science. 2020 Jun 19;368(6497):1335–1340. doi: 10.1126/science.aaz5143

Fig. 3. Characterization of antibody-resistant mutants.

Fig. 3.

(A) The minimum inhibitory concentration (MIC) of CR9114 and FI6v3 to individual viral mutants are shown. The MIC of CR9114 is in red and represented by the y-axis on the left. The MIC of FI6v3 is in blue and represented by the y-axis on the right. (B) The Spearman’s rank correlations (ρ) between the MIC measured from individual mutants and the relative resistance (against 10 μg/mL CR9114 antibody or 2.5 μg/mL FI6v3 antibody) computed from the profiling experiment (screening) are shown. The green dashed line represents the upper detection limit in A and B. Wild type is represented by the red “X”.