Fig. 1.

Micrographs of the heart (A), liver (B), and kidney (C) tissues in rats. Normal histoarchitecture of A1) heart, B1) liver, and C1) kidney tissues are seen. Monosodium glutamate (MSG)-treated rats show congestion, edema, and fiber discontinuity in A2) heart, congestion, microhemorrhage, and fatty degeneration in B2) liver and congestion, cloudy swelling and glomerular shrinkage in C2) kidney tissues. Oral administration of a low dose (100 mg kg^-1) caper fruit extract had no effects on A3) heart, B3) liver, and C3) kidney histopathological changes induced by MSG. Oral administration of a high dose (300 mg kg^-1) caper fruit extract reduced MSG-induced histopathological changes in A4) heart, B4) liver, and C4) kidney tissues. The MSG-induced histopathological changes in A5) heart, B5) live, and C5) kidney were attenuated by oral administration of quercetin (10.00 mg kg^-1). Oral administration of vitamin E (200 mg kg^-1) reduced MSG-induced histopathological changes in A6) heart, B6) liver, and C6) kidney tissues, (H & E, 400×)