Table III.
Association between Beclin-1 expression and clinicopathological characteristics in patients with non-small cell lung cancer (n=120).
| Beclin-1 expression | |||||
|---|---|---|---|---|---|
| Pathologic parameter | Cases, n | High | Low | χ2 | P-value |
| Sex | 0.46 | >0.05 | |||
| Male | 56 | 16 | 40 | ||
| Female | 64 | 22 | 42 | ||
| Smoking history | 2.62 | >0.05 | |||
| Yes | 54 | 13 | 41 | ||
| No | 66 | 25 | 41 | ||
| Age, years | 1.56 | >0.05 | |||
| ≤60 | 41 | 16 | 25 | ||
| >60 | 79 | 22 | 57 | ||
| Pathological stage | 6.54 | <0.05a | |||
| I | 59 | 25 | 34 | ||
| II | 42 | 10 | 32 | ||
| III | 19 | 3 | 16 | ||
| Lymph node metastasis | 4.53 | <0.05a | |||
| Positive | 45 | 9 | 36 | ||
| Negative | 75 | 29 | 46 | ||
| Pathological type | 0.89 | >0.05 | |||
| Adenocarcinoma | 83 | 28 | 55 | ||
| Squamous | 31 | 9 | 22 | ||
| Others | 6 | 1 | 5 | ||
| Degree of differentiation | 6.90 | <0.05a | |||
| Well | 26 | 12 | 14 | ||
| Moderate | 61 | 21 | 40 | ||
| Poor | 33 | 5 | 28 | ||
| Carcinoembryonic antigen, ng/ml | 1.99 | >0.05 | |||
| ≤5 | 55 | 21 | 34 | ||
| >5 | 65 | 17 | 48 | ||
a
Statistical significance (P<0.05).