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. 2020 Aug 6;10:24. doi: 10.5334/tohm.548

Table 3.

Causes of acquired choreas.

Etiology Disease

Pharmacological Acute drug-induced, Tardive chorea, Alcohol, Other toxins
Vascular Stroke, Subdural or Extradural Hematomas, Small vessel disease
Hematological Polycythemia vera, Essential thrombocythemia, Transitional myeloproliferative disease
Autoimmune SLE, APS, NMDAR encephalitis, Behcet’s disease, Sjögren syndrome, Celiac disease, IgLON5, D2R, GABAaR, and Neurexin-3 alpha
Endocrine/Metabolic Hyperthyroidism, Hypocalcemia, Hyper/Hyponatremia, Hyperglycemia, Hypomagnesemia, Uremia, Non-wilsonian hepatolenticular degeneration, Kernicterus
Nutritional Vitamin B12 and B1 deficiency
Demyelinating disorders Multiple Sclerosis, ADEM, Central pontine and extrapontine myelinolysis
Neoplastic Primary or Secondary
Paraneoplastic Anti-CRMP5, Anti-Hu, Anti-Ma, Anti-P/Q and N-type V-G calcium channel, Anti-NMDAR, Anti-LGI1, Anti-Caspr2
Infectious/Parainfectious Sydenham’s chorea, Bacterial, Viral, Spirochetal
Brain hypoxia Cardiac arrest, Respiratory insufficiency, Anesthetic complication, Hypothermia, CO Poisoning, Post pump chorea
Other Mastocytosis, Chorea gravidarum, Cerebral palsy

SLE: systemic lupus erythematosus; APS: anti-phospholipid syndrome; NMDAR: anti-n-methyl-d-aspartate receptor; ADEM: acute disseminated encephalomyelitis.