Table 2.
Correlation between disease recurrence and SFRP1 expression detected by IHC staining in patients with ampullary adenocarcinoma after curative resection.
| Expression of SFRP1 | P | ||
|---|---|---|---|
| Low | High | ||
| No recurrence, n (%)a | 10 (50%) | 1 (13%) | NS |
| Recurrence, n (%)a | 10 (50%) | 7 (87%) | |
| Delayed recurrence (after postoperative 12 months) | 4 | 2 | NS |
| Early recurrence (within postoperative 12 months) | 6 | 5 | 0.056 |
| Patterns of recurrencea,b | |||
| Liver metastasis | 3 | 3 | NS |
| Local recurrence | 5 | 5 | 0.061 |
| Peritoneal carcinomatosis | 1 | 3 | 0.015 |
| Bone metastasis | 5 | 0 | NS |
| Other metastasisc | 4 | 0 | NS |
SFRP1, secreted frizzled related protein 1; NS, not significant.
aExcluding two patients who died due to surgical complications and two patients who lost follow-up in NCKUH.
bSome patients developed more than one kind of metastases.
cIncluding brain, lung, and ovary metastases.