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Influence of the presence of Cys residues within an epitope on predicted MHC class I binding affinity
| No. of Peptides |
|||
|---|---|---|---|
| Epitope Status | With Cys | No Cys | Total |
| AU epitopes | |||
| Predicted nonbinders | 4 | 4 | 8 |
| Predicted binders | 10 | 59 | 69 |
| Total (p = 0.014) | 14 | 63 | 77 |
| A*02:01 epitopes | |||
| Predicted nonbinders | 4 | 0 | 4 |
| Predicted binders | 3 | 24 | 27 |
| Total (p = 0.0001) | 7 | 24 | 31 |
| Non-A*02:01 epitopes | |||
| Predicted nonbinders | 0 | 4 | 4 |
| Predicted binders | 7 | 35 | 42 |
| Total (p = 0.375) | 7 | 39 | 46 |
