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. 2020 Aug 6;10:13211. doi: 10.1038/s41598-020-70043-9

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(A,B) CD41 immunohistochemistry of human inflammatory cardiomyopathy. The CD41 antigen is stained green. CD41 positive cells are highlighted with black arrows. (C) Control antibody staining of human inflammatory cardiomyopathy specimen. No CD41 positivity is seen (D) Human inflammatory cardiomyopathy specimen incubated with LIBS-MPIO. MPIOs can be identified as golden pellets. (E) Human inflammatory cardiomyopathy specimen incubated with control-MPIO. (F) Quantification of LIBS-MPIO binding to a human inflammatory cardiomyopathy specimen showed significantly more binding of LIBS-MPIO than control-MPIO.