Table 2. Dispositions of hospitalizations for serious infections with and without opioid use disorder.
| Disposition | Opioid use disorder (N = 7,610) | No opioid use disorder (N = 87,739) | Total (N = 95,349) | Unadjusted odds ratio (95% CI) | p-Value | Adjusted odds ratio (95% CI) | p-Value |
|---|---|---|---|---|---|---|---|
| Home | |||||||
| All | 3,450 (45.3) | 55,390 (63.1) | 58,840 (61.7) | 0.49 (0.43, 0.54) | <0.001 | 0.38 (0.33, 0.43) | <0.001 |
| Without services | 2,625 (34.5) | 31,010 (35.3) | 33,635 (35.3) | 0.98 (0.87, 1.10) | 0.69 | 0.74 (0.64, 0.84) | <0.001 |
| With services | 825 (10.8) | 24,380 (27.8) | 25,205 (26.4) | 0.31 (0.26, 0.37) | <0.001 | 0.37 (0.30, 0.45) | <0.001 |
| Post-acute care facility (rehabilitation center, skilled nursing facility) | 2,120 (27.9) | 25,130 (28.6) | 27,250 (28.6) | 0.96 (0.84, 1.11) | 0.61 | 1.85 (1.57, 2.17) | <0.001 |
| Transferred to another acute care facility | 520 (6.8) | 3,935 (4.5) | 4,455 (4.7) | 1.62 (1.30, 2.02) | <0.001 | 0.90 (0.70, 1.16) | 0.41 |
| Patient-directed discharge | 1,450 (19.1) | 2,310 (2.6) | 3,760 (3.9) | 8.82 (7.43, 10.48) | <0.001 | 3.47 (2.80, 4.29) | <0.001 |
| Died | 70 (0.9) | 974 (1.1) | 1044 (1.1) | 0.84 (0.48, 1.46) | 0.53 | 0.97 (0.52, 1.80) | 0.92 |
Data are given as number (%). Services for home discharges include a home IV provider or being under the care of an organized home health service organization. Post-acute care facilities include skilled nursing facilities, intermediate care facilities, inpatient rehabilitation facilities, hospice facilities, long-term care hospitals, and psychiatric hospitals. National estimates generated using discharge weights computed for the 20% sample from the 2016 National Inpatient Sample. Adjusted odds ratios, 95% confidence intervals, and p-values were calculated using multivariable logistic regression models to reflect the odds of each disposition compared with all other dispositions in patients with opioid use disorder versus no opioid use disorder. Multivariable models were adjusted for age, sex, race/ethnicity, primary payer, median household income, Elixhauser Comorbidity Index, infection type, hospital size, hospital type, hospital region, elective versus non-elective admission, weekday versus weekend admission, and the number of major operating room procedures. Patient-directed discharge is coded as “against medical advice.”