Table 2.

Circulating white blood cells, neutrophil to lymphocyte ratio (NLR), H₂O₂ and risk of breast cancer.

	Cases/Controls	ORa	95% CI	ORb	95% CI
Neutrophils #, 103/μL
< 2.8	72/120	1.0		1.0
2.8–3.7	100/123	1.26	0.85–1.89	1.17	0.77–1.79
> 3.70	127/113	1.66	1.12–2.47	1.40	0.92–2.15
P-trend			0.002		0.02
Neutrophils %
< 48.6	54/121	1.0		1.0
48.6–57	109/127	1.88	1.24–2.86	1.79	1.17–2.78
> 57	136/111	2.42	1.60–3.68	2.14	1.39–3.32
P-trend			< 0.001		< 0.001
Monocytes #, 103/μL
< 0.3	82/131	1.0		1.0
0.3–0.44	114/108	1.59	1.08–2.34	1.61	1.06–2.43
> 0.44	103/117	1.43	0.97–2.11	1.36	0.90–2.07
P-trend			0.18		0.38
Monocytes %
< 5.87	118/125	1.0		1.0
5.87–7	108/150	0.86	0.60–1.23	0.95	0.65–1.40
> 7	73/84	1.02	0.68–1.54	1.06	0.68–1.64
P-trend			0.16		0.17
Lymphocytes #, 103/μL
< 1.9	136/133	1.0		1.0
1.9–2.5	107/119	0.85	0.59–1.22	0.93	0.63–1.36
> 2.5	56/104	0.52	0.34–0.78	0.54	0.35–0.83
P-trend			< 0.001		0.001
Lymphocytes %
< 31	141/124	1.0		1.0
31–39	106/123	0.79	0.55–1.13	0.87	0.59–1.27
> 39	52/111	0.44	0.29–0.67	0.51	0.33–0.79
P-trend			< 0.001		< 0.001
NLR
< 1.26	58/117	1.0		1.0
1.26–1.85	101/121	1.64	1.08–2.49	1.50	0.97–2.33
> 1.85	139/117	2.19	1.46–3.30	1.93	1.26–2.97
P-trend			< 0.001		< 0.001
H2O2 #, ng/mL
< 284	78/52	1.0		1.0
284–517	29/48	0.42	0.23–0.75	0.42	0.22–0.79
> 517	19/49	0.25	0.13–0.47	0.26	0.13–0.51
P-trend			< 0.001		< 0.001

^aAdjusted for age at diagnosis (cases) and age at interview (controls).

^bFurther adjusted for age at menarche, parity, menopausal status, and BMI.