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. 2020 Aug 6;10:13203. doi: 10.1038/s41598-020-70077-z

Table 4.

Neutrophil to lymphocyte ratio (NLR) and risk of breast cancer according to total cholesterol and H2O2 levels.

Total cholesterol < 193 mg/dL Total cholesterol ≥ 193 mg/dL
Ca/Co ORa 95% CI ORb 95% CI Ca/Co ORa 95% CI ORb 95% CI
NLR
< 1.26 18/29 1.0 1.0 38/87 1.0 1.0
1.26–1.85 22/32 1.10 0.49–2.47 0.91 0.39–2.10 75/85 1.99 1.20–3.34 1.96 1.14–3.38
> 1.85 48/48 1.59 0.78–3.32 1.41 0.66–3.04 85/62 3.01 1.80–5.10 2.79 1.60–4.91
P-trend 0.03 0.09  < 0.001  < 0.001
H2O2 < 284 ng/mL H2O2 ≥ 284 ng/mL
Ca/Co ORa 95% CI ORb 95% CI Ca/Co ORa 95% CI ORb 95% CI
NLR
< 1.26 9/17 1.0 1.0 9/22 1.0 1.0
1.26–1.85 28/9 5.31 1.76–17.31 5.95 1.71–23.01 20/36 1.68 0.64–4.66 1.75 0.61–5.32
> 1.85 41/21 3.65 1.38–10.22 3.30 1.12–10.40 19/36 1.53 0.58–4.24 1.74 0.59–5.43
P-trend 0.016 0.056 0.31 0.31

aAdjusted for age at diagnosis (cases) and age at interview (controls).

bFurther adjusted for age at menarche, parity, menopausal status, and BMI.