Table 4.
Neutrophil to lymphocyte ratio (NLR) and risk of breast cancer according to total cholesterol and H2O2 levels.
Total cholesterol < 193 mg/dL | Total cholesterol ≥ 193 mg/dL | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Ca/Co | ORa | 95% CI | ORb | 95% CI | Ca/Co | ORa | 95% CI | ORb | 95% CI | |
NLR | ||||||||||
< 1.26 | 18/29 | 1.0 | 1.0 | 38/87 | 1.0 | 1.0 | ||||
1.26–1.85 | 22/32 | 1.10 | 0.49–2.47 | 0.91 | 0.39–2.10 | 75/85 | 1.99 | 1.20–3.34 | 1.96 | 1.14–3.38 |
> 1.85 | 48/48 | 1.59 | 0.78–3.32 | 1.41 | 0.66–3.04 | 85/62 | 3.01 | 1.80–5.10 | 2.79 | 1.60–4.91 |
P-trend | 0.03 | 0.09 | < 0.001 | < 0.001 |
H2O2 < 284 ng/mL | H2O2 ≥ 284 ng/mL | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Ca/Co | ORa | 95% CI | ORb | 95% CI | Ca/Co | ORa | 95% CI | ORb | 95% CI | |
NLR | ||||||||||
< 1.26 | 9/17 | 1.0 | 1.0 | 9/22 | 1.0 | 1.0 | ||||
1.26–1.85 | 28/9 | 5.31 | 1.76–17.31 | 5.95 | 1.71–23.01 | 20/36 | 1.68 | 0.64–4.66 | 1.75 | 0.61–5.32 |
> 1.85 | 41/21 | 3.65 | 1.38–10.22 | 3.30 | 1.12–10.40 | 19/36 | 1.53 | 0.58–4.24 | 1.74 | 0.59–5.43 |
P-trend | 0.016 | 0.056 | 0.31 | 0.31 |
aAdjusted for age at diagnosis (cases) and age at interview (controls).
bFurther adjusted for age at menarche, parity, menopausal status, and BMI.