Table 1. Characteristics of study participantsa.
| All participants | Participants without hypertension | Participants with hypertension | p b | |
|---|---|---|---|---|
| n | 1108 | 414 | 694 | |
| Female sex n (%) | 546 (49) | 230 (56) | 316 (46) | < 0.001 ### |
| Age (years) | 70.4 ± 5.5 | 69.0 ± 5.2 | 71.1 ± 5.5 | < 0.001 # |
| BMI (kg/m2) | 28.7 ± 4.5 | 27.3 ± 4.0 | 29.6 ± 4.6 | < 0.001 # |
| Systolic blood pressure (mmHg) | 128.5 ± 19.6 | 119.8 ± 13.8 | 133.7 ± 20.8 | < 0.001 # |
| Diastolic blood pressure (mmHg) | 74.0 ± 10.0 | 71.8 ± 8.3 | 75.4 ± 10.7 | < 0.001 # |
| eGFR (ml/min/1.73 m2) | 77.9 (67.3; 87.8) | 81.4 (72.0; 89.7) | 75.3 (64.2; 85.5) | < 0.001 ## |
| sUmod (ng/ml) | 152.5 (110.1; 207.7) | 176.9 (126.5; 228.4) | 138.1 (99.2; 190.4) | < 0.001 ## |
| Previous stroke n (%) | 46 (4) | 5 (1) | 41 (6) | 0.21 ### |
| Previous myocardial infarction n (%) | 65 (6) | 16 (4) | 49 (7) | < 0.001 ### |
| Current smoking n (%) | 81 (7) | 41 (10) | 40 (6) | 0.03 ### |
| n | 1097 | 409 | 688 | |
| Renin (ng/l) | 11.0 (5.3; 22.4) | 8.8 (5.1; 15.6) | 12.8 (5.4; 30.9) | < 0.001 ## |
| Aldosterone (ng/l) | 37.2 (24.0; 56.0) | 38.0 (24.0; 56.0) | 36.0 (25.2; 54.0) | 0.81 ## |
| n | 618 | 220 | 398 | |
| CT-proET-1 (pmol/l) | 51.5 (44.6; 61.2) | 47.6 (42.8; 54.3) | 53.8 (46.5; 64.3) | < 0.001 ## |
a Mean ± standard deviation, median (first quartile; third quartile), or number of participants (proportion in %)
b The p value is related to the null hypothesis of no differences between participants with and without arterial hypertension
# T-test
##Mann-Whitney U-test
###Chi-square test.