Figure 1. Significant correlations of 3D analysis data, CTG expansion size, and phenotype in DM1 myoblasts.

(A) Correlation between CTG repeat expansion and RNA foci number. The 95% CI for the Pearson correlation coefficient was 0.222–0.986. (B) Correlation between CTG repeat expansion and percentage of cells presenting cytoplasmic RNA foci. The 95% CI for the Pearson correlation coefficient was 0.559–0.994. (C) Correlation between RNA foci number and % of cells presenting cytoplasmic RNA foci. The 95% CI for the Pearson correlation coefficient was 0.263–0.987. (D) Correlation between % of cells presenting RNA foci and % of cells presenting cytoplasmic RNA foci. The 95% CI for the Pearson correlation coefficient was 0.105–0.983. (E) Correlation between the RNA foci area (µm²) and the presence of cytoplasmic RNA foci. The 95% CI for the Pearson correlation coefficient was 0.085–0.982. (F) Correlation between age at onset of the disease and the presence of cytoplasmic RNA foci. The 95% CI for the Pearson correlation coefficient was −0.979 to −0.019. rep exp = repeat expansion; n = number; cyto = cytoplasm.