Table 1. mRNAs of conserved ATP synthetase components are localized to mitochondria in respiratory and CHX conditions.
ATP complex gene conservation was obtained from published annotation (Rühle and Leister, 2015) and we obtained data of CHX-dependent mitochondrial localization from proximity ribosomal profiling data (Williams et al., 2014). The CHX-dependent localization data were consistent with our study. Respiratory-specific localization was determined in this study.
| Complex | Subunit | Gene | Mitochondrial localization | Respiratory specific localization | ||
|---|---|---|---|---|---|---|
| -CHX | +CHX | |||||
| Conserved from bacteria to eukaryote | F1 | α | ATP1 | no | yes | yes |
| β | ATP2 | no | yes | yes | ||
| γ | ATP3 | no | yes | yes | ||
| OSCP/δ | ATP5 | no | yes | NA | ||
| ε | ATP16 | no | no | NA | ||
| F0 | b | ATP4 | no | yes | NA | |
| non-conserved | all the others | no | no | NA (ATP7: no) | ||
| Rühle and Leister, 2015 | Williams et al., 2014 | This study | ||||