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. 2020 Aug 7;15(8):e0228002. doi: 10.1371/journal.pone.0228002

Fig 1. CTDSP1 regulates irinotecan sensitivity in colon cancer cell lines.

Fig 1

A, Cell lysates from four colon cancer lines, HCT15, DLD1, LoVo and HT29, were immunoblotted with anti-CTDSP1 and anti-β-actin. B, HCT116 and HT29 cells were treated with 2.5 μM SN-38 and harvested after 90 and 180 min. Cell lysates were immunoblotted with anti-topoI and anti-β-actin. C, HCT116 and HT29 cells were treated with various concentrations of SN-38 and clonogenic assays were performed to determine the relative number of colonies.