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. 2020 Jul 2;107(2):330–341. doi: 10.1016/j.ajhg.2020.06.004

Figure 7.

Figure 7

Pups Obtained upon ICSI using the Spermatozoa from Dnah8-KO Male Mice

(A) Development of ICSI embryos. Fourteen (17.3%) of the 81 oocytes injected with the spermatozoa from Dnah8-KO (Dnah8em1/em1) male mice developed to the two-cell stage, and three pups were obtained after embryo transfer. ICSI data from the use of sperm from wild-type male mice are shown as controls.

(B) The pups obtained from ICSI using the spermatozoa from Dnah8-KO male mice.

(C) Genotyping of these pups. All of the pups carried the heterozygous Dnah8-mutated allele. KO denotes the mutated allele and WT denotes the wild-type allele.