Fig. 2.

a Osteosarcoma. CT imaging demonstrates a partially mineralized soft tissue mass located in the anterior commissure. b Histologic sections demonstrate malignant spindle cells with osteoblastic differentiation, including bone matrix deposition. c Embryonal rhabdomyosarcoma. Histologic section showing a submucosal proliferation of atypical spindled to round neoplastic cells with subepithelial condensation and scattered cells showing features of rhabdomyoblastic differentiation. d Immunohistochemical stains show strong immunoreactivity for desmin and MyoD1. e Well-differentiated liposarcoma. CT imaging demonstrates a mass involving the epiglottis/vallecula. f Histologic section demonstrating a neoplasm composed of adipose tissue and loose fibrous stroma containing atypical spindle cells characteristic of well-differentiated liposarcoma