Table 1.

Summary of relevant clinical and molecular features of reported LGPSC cases

	Sex/age	p16	p53	Ki67	HPV-DNA	Smoke	Initial pathologic diagnosis	Recurrence	Nodal metastasis	Follow-up
Lewis 2015 [5]	F/47	50%	50%	5–60%	Negative	NA	Schneiderian papillomas	Multiple	Yes	18 years (DOD)
Jeong 2017 [6]	F/42	Peripheral	50%	10%	NA	NA	Schneiderian oncocytic papilloma	No	No	21 months
Brown 2018 [7]	F/65	NA	NA	NA	NA	NA	Schneiderian papilloma and nasal polyps	1 month	No	3 months
Williamson 2019 [8]	F/56	negative	NA	15%	Negative	NA	Transitional proliferation with inverted growth	13 months	No	>12 months
Our case	M/68	70% (peripheral)	50%	50%	Negative	Former heavy	None	No	No	16 months