Fig. 2.

Cryo-EM structures of three kinds of CV-A10 particles at pH 7.4 and pH 5.5. (A) Density map of a mature CV-A10 particle at pH 7.4 (3.1 Å) (Upper) and a close-up view of the pocket region within the canyon (Lower). The density map is colored by radius, as indicated by the legend bar. The atomic model is shown in ribbons and colored by chains (VP1, blue; VP2, green; VP3, red). The “pocket factor” is shown as sticks, and the corresponding density map (mesh) is shown at 2.5σ contour. (B–F) Density maps and zoom-in views of atomic models of CV-A10 particles at different states/conditions, shown in the same style as in A.