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Effect of pretreatment with TMP on: (A) COX-1, (B) PGE2 concentrations in indomethacin-induced gastric ulcer in rats. Data are presented as mean ± S.D. (n = 6) a and b: statistically significant from the corresponding control and indomethacin group, respectively, at P < 0.05 using one-way analysis of variance (ANOVA) followed by Tukey’s as a post-hoc test.
