Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jul 17;117(31):18744–18753. doi: 10.1073/pnas.2002738117

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 the Author(s). Published by PNAS.

This open access article is distributed under Creative Commons Attribution License 4.0 (CC BY).

PMC Copyright notice

Fig. 4. — MorphEUS accurately predicts pathways of action of compounds when blinded to mechanism of action. (A) cKNN profiles of broad drug categories and (B) individual drugs for compounds with anti-TB activities (unk, unknown). Each column corresponds to a different compound or treatment dose. From left to right, joint dose profile (JP) for DG167, JSF-3825, JSF-2019; high dose profile (HD) for JSF-2019; and low dose (LD) profile for JSF-2019: n = 7,300, 7,160, 7,742, 7,742, 5,150, and 2,592 respectively. The most similar drug for each MorphEUS classification is indicated by the red asterisk.