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. 2020 Jul 20;117(31):18701–18710. doi: 10.1073/pnas.2005726117

Fig. 3.

Fig. 3.

YY1 responsive element in HTLV-1 LTR maps to the R region. (A) Schematic of LTR truncation mutants. (B) Similar assay as Fig. 1B using LTR truncation mutants. Relative luciferase expression was calculated by first dividing the firefly luciferase (FL) signal by the Renilla luciferase signal in a given cell, and the resulting ratio was then normalized to the ratio obtained from cells transfected with LTR-FL (set to 1). Results shown are means ± SEs from three independent experiments performed in duplicate. (C) Schematic of HTLV-1 R region 3′ truncation mutants. (D) Similar assay as Fig. 1B using HTLV-1 R region 3′ truncation mutants. Results shown are means ± SEs from three independent experiments performed in duplicate. (E) Schematic of HTLV-1 R region serial deletion mutants. (F) Similar assay as Fig. 1B using HTLV-1 R region serial deletion mutants. Results shown are means ± SEs from three independent experiments performed in duplicate.