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. 2020 Aug 7;10:13343. doi: 10.1038/s41598-020-70231-7

Figure 8.

Figure 8

Implantation of AdIL-17A transduced 4T1 tumor cells mobilizes immune cells to the peripheral blood but suppressed infiltration into the lung and tumor sites. Mice were inoculated with AdIL-17A- or Addl-transduced 4T1 tumor cells. Blood samples were collected at days 4, 7, and 14, and mice were sacrificed at day 17 to harvest tissues. The immune profile in blood, lung, and tumor was determined by flow cytometric analyses (n = 10 per group). (A) The number of CD4 and CD8 T cells, NK cells, and B cells in peripheral blood samples at days 4, 7, and 14. (B,C) The number of CD4 and CD8 T cells, NK cells and B cells in the lung and tumor sites at day 17. *P < 0.05; **P < 0.01; ***P < 0.001 compared to Addl using unpaired Student’s t-test.